Another notable designation is offensive lineman Ben Bartch, who will begin training camp on the active/non-football injury (NFI) list. Bartch is considered the frontrunner to replace Aaron Banks as the team’s starting left guard following Banks’ departure in free agency.

In addition to the two wide receivers, four other players were also included on the PUP list: Andre Dillard, Yetur Gross-Matos, Malik Mustapha, and Curtis Robinson. Meanwhile, Ben Bartch and George Odum have been placed on the Active/Non-Football Injury list.

The San Francisco 49ers enter training camp with Super Bowl aspirations after a disappointing season that left questions about their offensive identity. With Robert Saleh back as defense coordinator,

After losing starting offensive linemen Aaron Banks and Jaylon Moore, the 49ers are counting on certain backups to step up this year.

The San Francisco 49ers will be without a quarterback early in training camp. Kurtis Rourke is opening camp on the non-football injury list. The seventh-round rookie from Indiana is working his way back from an ACL tear in his right knee. It's his second such injury.

The Niners are paying Brock Purdy to be elite, and he does have Christian McCaffrey and George Kittle, but if Jennings holds out and both Pearsall and Aiyuk are injured, their best wide receiver would be Demarcus Robinson. No disrespect to Robinson, but it'd be tough for any quarterback to thrive under those circumstances.

Deebo Samuel is gone -- he requested a trade, so the 49ers sent him to the Washington Commanders for a fifth-round pick. And now, Samuel reportedly has just 8 percent body fat.

Head coach Kyle Shanahan didn't seem concerned about the San Francisco 49ers injury situation after 15 players missed mandatory minicamp.