San Francisco 49ers placed six players on the Active/Physically Unable to Perform list and two on the Active/Non-Football Injury list ahead of training camp.

The San Francisco 49ers have officially signed the final member of their 2025 rookie class—second-round pick Alfred Collins—ending any speculation that the defensive tackle might hold out when training camp practices begin next week.

In other words, the 49ers and Collins both need each other. It's an added bonus that Collins' rookie contract will also help many of his draft classmates get the money they deserve. Still, at the time of this writing,

The second-round standoff, which involves Rams TE Terrance Ferguson, could be coming to an end after the 49ers signed Alfred Collins.

The San Francisco 49ers have reportedly signed former Texas defensive tackle Alfred Collins to his rookie contract. Selected with the No. 43 overall pick

The San Francisco 49ers have signed most of their rookie class, but defensive lineman Alfred Collins has yet to agree to his contract.

The next big domino in the second round has fallen: 49ers’ second-round pick Alfred Collins, the No. 43rd overall selection, reached agreement tonight on a four-year, $10.3 million deal that includes over $9 million guaranteed and now is expected to trigger multiple second-round signings,

Pro Football Focus (PFF) contributor Dalton Wasserman recently identified each NFC team's top offseason decision. For the San Francisco 49ers, it was a significant overhaul of the defensive line that stood out as their most impactful move.