Alushin's lab specializes in understanding the cytoskeleton—the network of protein filaments, including actin, that form a cell's infrastructure. Actin serves many functions: it provides cells with an ...

In all eukaryotic cells, actin protein assembles to form a network of thin filaments that spread throughout the cell. The actin filaments give the cell its structure, enable the cell to move, and ...

Microtubules are the largest type of filament, with a diameter of about 25 nanometers (nm), and they are composed of a protein called tubulin. Actin filaments are the smallest type, with a ...

Sep. 28, 2023 — Actin filaments are dynamic protein-fibers in the cell built from single actin proteins. Many cellular functions, including cell movement, are regulated by constant filament ...

But Portnoy, who joined UPenn’s medical school in 1988, had found he could block this cell-to-cell spread by chemically inhibiting the polymerization of actin, a protein that cells use to build an ...

Actin proteins group together to form a network of thin filaments that spread throughout a cell. This actin network is dynamic, meaning that the filaments can either grow or shrink to fit the ...

The interaction of myosin and actin proteins is at the core of our current understanding of sarcomere shortening. How does this shortening happen? It has something to do with a sliding interaction ...

Scientists reveal how filopodia help cancer spread. The breakthrough could improve treatments that stop cancer cells from invading tissues.

An effective response to a foreign invasion depends on the ability of cells to mobilize immediately. The cytoskeletal protein actin is essential for cell mobility, as well as the changes in cell shape ...

Alushin's lab specializes in understanding the cytoskeleton—the network of protein filaments, including actin, that form a cell's infrastructure. Actin serves many functions: it provides cells ...