The human EphA3 gene was discovered in a pre-B acute lymphoblastic leukemia (pre-B-ALL) using the EphA3-specific monoclonal antibody (mAb), IIIA4, which binds and activates both human and mouse EphA3.

Manipulating the immune system to treat cancer has generated phenomenal responses in some patients, including complete cures, ...

Acute lymphoblastic leukemia has the highest survival among ... Doctors used chemotherapy and immunotherapy combined to enhance cure rates. The results were so promising the trial ended so the ...

Draft guidance published for an immunotherapy treatment that could prevent blood cancer from returning in adults who've responded well to initial therapy.

A retrospective analysis showed improved overall survival (OS) with Orca-T compared with post-transplant cyclophosphamide in ...

adolescents and young adults with acute lymphoblastic leukemia or non-Hodgkin's lymphoma MedImmune LLC NCT01508312 Brentuximab vedotin (SGN-35) in transplant eligible patients with relapsed or ...

Get Instant Summarized Text (Gist) Scientists have redesigned asparaginase, a treatment for acute lymphoblastic leukemia, to reduce severe side effects like blood clots and liver damage. By using ...

Children under 5 years have the highest risk of developing acute lymphoblastic leukemia (ALL). However, it can also affect adults, typically over the age of 50. Around 60% of cases are in children.

It can be more difficult to treat relapsed or refractory acute lymphoblastic leukaemia (ALL ... CAR T-cell therapy is a type of immunotherapy. CAR stands for chimeric antigen receptor. CAR T-cell ...