Clathrin-coated vesicles (CCVs) are proposed to assemble through the binding of adaptor protein complex 2 (AP2) and the coat protein clathrin to cargo proteins destined for internalization ...

The research is published in the journal Nature Communications. During clathrin-mediated endocytosis, adaptor proteins bind to the cell membrane and to the protein clathrin, assisting in engulfing ...

“This work has made the most beautiful simplification of all this big complex mess. Basically, they identified and pinpointed the specific protein involved in the switching decision and explain how ...

immunocytochemistry and biochemistry results argue against the idea that this protein serves as an adaptor to link PKCε to CaV2.2. It should be noted that an important tool in our study ...