The SARS-CoV-2 pandemic interrupted much respiratory research. Respiratory clinical academics joined colleagues in providing clinical care, and global research efforts were directed to finding new ...

New, more effective anti-inflammatory drugs are needed to treat asthma. Anti-eosinophil approaches include targeting cytokines (anti-IL-4, -13, and -5), their receptors (βc) or chemokine ...

The goal of treatment is to reduce eosinophils in the airways, control inflammation, improve asthma symptoms, and reduce the frequency and severity of asthma attacks. Most people with eosinophilic ...

Discovery of a novel form of cell death in eosinophils, white blood cells linked to triggering asthma, could lead to a new treatment for the disease, says respiratory physician Wen Li, director of ...

Depemokimab is a follow-up to GSK's Nucala (mepolizumab), a once-monthly IL-5 inhibitor approved for severe asthma, CRSwNP, ...

Of four treatment response measures recorded at 6 months of mepolizumab treatment, an Asthma Control Questionnaire score was ...

His spirometry, elevated blood eosinophil count, and elevated FENO suggested that patient had eosinophilic asthma ... options of biologic therapy options, including anti IgE, anti IL5, and ...

The firm is expected to file with regulators its new anti-eosinophil monoclonal antibody benralizumab, a treatment for severe asthma, before the end of 2016. Join the conversation, on Tuesday 28th ...

Areteia Therapeutic’s CEO, Jorge Bartolome, shared his company’s novel and first oral drug development to treat eosinophilic ... current treatment approaches for severe asthma are primarily ...

Asthma affects more than 300 million people ... and Drug Administration and European Medicines Agency for the treatment of severe eosinophilic asthma. These biologics lower eosinophil numbers ...

More information: Maria Gioulvanidou et al, Vectorized Human Antibody-Mediated Anti-Eosinophil Gene Therapy, Human Gene Therapy (2024). DOI: 10.1089/hum.2024.165 Provided by Mary Ann Liebert, Inc ...

The studies of mepolizumab have shown that this treatment was safe and well ... anti-inflammatory drugs are needed to treat asthma. Anti-eosinophil approaches include targeting cytokines (anti ...