Endogenous prostaglandins (PGs) and their receptors are found in the aqueous humor drainage pathways. Endogenous PGs biochemically regulate the matrix metalloproteinases and tissue inhibitors of ...

However, problems arise when the drainage system becomes blocked or less efficient. Imagine your eye as a sink with an open ...

Trabeculectomy: A surgical procedure that creates a new drainage pathway for aqueous humor to lower IOP, often involving the creation of a filtering bleb. Aqueous Humor: The clear fluid produced ...

Available in single or combination formulations, they regulate liquid production and drainage ... aqueous humor, subsequently reducing intraocular pressure (IOP). LPI creates an alternative ...

For decades it was thought that endogenous PGs were solely involved in inflammatory processes. The concept that low doses of PGs applied topically to the eye could reduce IOP without causing ...