Autophagy is a cellular degradation pathway for the clearance of damaged or superfluous proteins and organelles. The recycling of these intracellular constituents also serves as an alternative ...

The term 'autophagy' was chosen to distinguish the lysosomal degradation ... to analyse mammalian cells that express autophagy proteins tagged with fluorescent markers. Time-lapse studies provide ...

which are linked to imbalances in lipid and protein production and degradation. Furthermore, improving autophagy function has the potential to slow cellular ageing by preserving organelle quality ...

The autophagy process degrades and recycles malformed proteins or worn-out organelles using lysosomal machinery. In the past, autophagy has been shown to act only as an adaptive response to extreme ...

demonstrating the proficiency of MZ1 to position the target protein for degradation and the favorability of the target protein for ubiquitination by UBE2R1. The importance of degraders for ...

And it also degrades and recycles proteins when cells become starved. As a result, it plays a role in maintaining the constant environment in the living body. *2 selective autophagy Traditionally, ...

Metastatic progression is driven by the expression and stabilization of pro-metastatic proteins. This study reveals how ...

which are linked to imbalances in lipid and protein production and degradation. Furthermore, improving autophagy function has the potential to slow cellular aging by preserving organelle quality ...

X-linked myopathy with excessive autophagy (XMEA) is a rare disease for which pre-clinical models lack, challenging the ...

Autophagy is a degradation process of proteins in cells during a state of nutrient starvation. It is a basic and primary function found in almost all eukaryotes, from yeasts to humans. Since ...