A research team affiliated with UNIST has unveiled an innovative technology to eliminate drug-resistant cancer cells using ...

whereas the inhibition of autophagy can sensitize cancer cells to chemotherapy to promote p53-induced apoptosis. Thus, manipulation of autophagy can determine cell-fate decisions in clinical settings.

Abstract Autophagy is a crucial quality control mechanism that degrades damaged cellular components through lysosomal fusion with autophagosomes ...

it is possible to artificially trigger autophagy, which could then enable the degradation of deposits in neurodegenerative diseases such as Alzheimer's, or support cancer therapies. Recycling ...

Liver Health: Autophagy may prevent damage caused to the liver by alcohol, drugs, or conditions known as fatty liver. Cancer: While autophagy may inhibit early tumor growth by removing damaged ...

Oral cancer is an increasingly prevalent disease ... the research team found that chemo-resistant TCOs rely on the activation of autophagy (or 'internal recycling') and cholesterol biosynthesis ...

Its disruption is linked to many known diseases in humans, such as Alzheimer's, Parkinson's, and cancer. Though understanding autophagy in detail is important from medical and biological ...

Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain.

Dr. Weickert will present Pacylex at the OBIO® Investment Summit and Early Technology Showcase February 5-7, 2025, at the Arcadian Court & Loft, Toronto Mr. Kamdar will present Pacylex at the PWMC ...

Tongue cancer (TC) cells can enter a chemo-resistant state by activating pathways related to autophagy and cholesterol synthesis, report researchers from Institute of Science Tokyo. Using a large ...