If targeted delivery to brain parenchyma is not the goal, alternative methods for crossing the blood–cerebrospinal fluid barrier may be considered or drugs may be introduced directly in the ...

More information: Miika Martikainen et al, VLDLR mediates Semliki Forest virus neuroinvasion through the blood-cerebrospinal fluid barrier, Nature Communications (2024). DOI: 10.1038/s41467-024 ...

Reference: Martikainen M, Lugano R, Pietilä I, et al. VLDLR mediates Semliki Forest virus neuroinvasion through the blood-cerebrospinal fluid barrier. Nat Commun. 2024;15(1):10718. doi: 10.1038/s41467 ...

In 10 male patients, forty-four to seventy-eight years of age, with varying degrees of respiratory insufficiency, blood and cerebrospinal fluid were drawn simultaneously from the brachial artery ...

Upon systemic infection from mosquito bites, Semliki Forest virus causes mild blood viremia before finding ... system by first entering the cerebrospinal fluid and then binding to a specific ...