The location of embryonic lymph node development is determined by the initial clustering of lymphoid tissue–inducer (LTi) cells. Here we demonstrate that both the chemokine CXCL13 and the ...

A newly defined threshold for the concentration of the cytokine CXCL13 may improve the diagnosis of neuroborreliosis.

In a small, phase 1 study, a first-generation anti-CD40L monoclonal antibody was investigated in persons with multiple sclerosis. 14 However, this study was terminated early owing to ...

DRAWN BY CHEMICAL ATTRACTION A team led by UCSF scientists has determined the mechanism that draws the immune system's B cells toward T cells, needed to launch an antibody response after exposure ...

A recent study posted to the bioRxiv* preprint server illustrated that specific chemokine antibodies aid in recognizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) convalescent ...

Breast cancers and melanomas release relatively small quantities of CXCL13. However, if these tumor cells spread to the lung, they can trigger clot formation by releasing CXCL13 and locally ...

Blood clots form in response to signals from the lungs of cancer patients -- not from other organ sites, as previously thought -- according to a preclinical study. Clots are the second-leading ...