The answer lies in transcription factors. Experiments have shown ... a higher level of control over genes involved in cell development and differentiation. The cells of higher organisms exhibit ...

Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...

to the inactivation of FOXO transcription factors. This scenario promotes proliferation and inhibits differentiation. In the absence of SLP65, most cells remain in a proliferative state ...

Andrew Teschendorff, Professor at the Chinese Academy of Sciences, is developing computational systems-biological tools to ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements.

Nearly 60,000 people are diagnosed with oral cancer in the U.S. every year, according to the American Cancer Society, and the rate of new cases continues to rise.

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

UC San Diego researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into oral cancer at the earliest stages of the disease ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive ...