Cerebrospinal fluid, or CSF, is a clear, colorless liquid that plays a crucial role in maintaining the health and function of ...

Deep in the brain, sheets of tissue known as the choroid plexus produce cerebrospinal fluid (CSF) and act as a protective ...

Choroid plexus tumors are rare. They develop in the choroid plexus, a network of cells lining the brain’s ventricles. Tumors in this area can disrupt the flow and production of CSF, leading to ...

After further investigation, it was found that the loss of SOX9 function led to an abnormal increase in hyperpermeability of the blood-CSF barrier. In the normal case, the choroid plexus restrains ...

The choroid plexus is essential for CSF production and plays a key role in maintaining brain homeostasis, primarily through the blood-CSF barrier. Studies have also increasingly highlighted its ...

However, prior to this study, little was known about the roles the choroid plexus and CSF play in brain repair after injury due to a lack of available adult animal models.

Besides producing CSF, the choroid plexus may have a more direct role in clearing amyloid, Chiang pointed out. "The transporters, lipoprotein receptor-related proteins 1 and 2, ...

Choroid plexus tissue, anchored in each of the brain's ventricles and bathed in cerebrospinal fluid, is a small but influential player in the brain. It's now been spatially inventoried with single ...

Lehtinen has shown that the choroid plexus regulates brain development, by secreting instructive cues into the CSF, and provides a protective brain barrier in early life, preventing unwanted cells ...

Choroid plexus signals regulate stem cells Fiona Doetsch's group uncovered that the choroid plexus secretes a wide variety of important signaling factors in the CSF, which are important for stem ...

CSF is made of water, proteins, sugars, ions and neurotransmitters. It is primarily produced by a network of cells called the choroid plexus, which is located in the brain’s ventricles, or cavities.

More information: Ya'el Courtney et al, Choroid plexus apocrine secretion shapes CSF proteome during mouse brain development, Nature Neuroscience (2025). DOI: 10.1038/s41593-025-01972-9 . Journal ...