small molecules to directly inhibit the two key proteases in the coagulation cascade: thrombin and factor Xa (FXa). The recent approval of dabigatran etexilate for the prevention of venous ...

Factor XIa Inhibitor: A type of anticoagulant that specifically targets and inhibits factor XIa, a protein involved in the coagulation cascade. Atrial Fibrillation: An irregular and often rapid ...

The ability to inhibit both clot-bound and free thrombin ... its enzymatic activity and can continue to stimulate the coagulation cascade. [12] Dr. Gulseth has been a paid consultant to Aventis ...

Moreover, platelets, which play a central role in the coagulation cascade, release numerous factors that stimulate or inhibit angiogenesis. In addition elements of the coagulation cascade act as ...

Sponsored by: Diagnostica Stago, Inc. Laboratory testing for coagulation factor deficiencies and inhibitors is important for diagnosing and monitoring inherited and acquired coagulopathies and for ...