The cytoskeleton of eukaryotic cells is made of filamentous proteins ... All cytoskeletons consist of three major classes of elements that differ in size and in protein composition.

Alushin's lab specializes in understanding the cytoskeleton—the network of protein filaments, including actin, that form a cell's infrastructure. Actin serves many functions: it provides cells with an ...

For example, humans alone have over 20 different kinds of integrins. Integrins link the actin cytoskeleton of a cell to various external structures. The cytoplasmic portion of each integrin ...

Structures inside cells influence everything from individual cell movement to an organism’s metabolism. They include the cytoskeleton, a dynamic internal protein network that gives cells their shape ...

Just like your body has a skeleton, every cell in your body has a skeleton—a cytoskeleton to be precise. This provides cells with mechanical resilience, as well as assisting with cell division.

A properly functioning cytoskeleton is needed for a wide variety of cellular events ranging from cell shape to cell signaling and migration/metastasis. We use multidisciplinary approaches to study ...

We aim to understand the molecular logic behind the dynamics of the actin cytoskeleton at endocytic sites and how disturbances in this process affect physiology and disease progression. Leonardo is ...

Approximately 15% of the proteins produced in our bodies are destined for the surface of our cells. Remarkably ... to elucidate the interplay of clathrin structures with the actin cytoskeleton and ...