These cell proteins, called transcription factors, help determine which ... At this point, RNA polymerase begins moving down the DNA template strand in the 3' to 5' direction, and as it does ...

Eukaryotic RNA polymerases use a number of essential cofactors (collectively called general transcription factors ... the DNA double helix unwinds and RNA polymerase reads the template strand ...

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene ...

Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...

Transcription factors are proteins that can bind to DNA and affect the expression of genes; some are known as master regulators that can have a wide impact | Genetics And Genomics ...

In bacteria, researchers have long known that transcription begins when RNAP clamps onto a DNA strand and initiates ... something like it (an RNAP release factor, so to speak)—exists not only ...

Knowing where the mRNA begins formation on the DNA strand is a significant part ... of the gene that becomes an mRNA. Thus, transcription-factor proteins can bind to several different sections ...

The transcription factor regulatory network in Pseudomonas aeruginosa is complex and involves multiple regulators that respond to various environmental signals and physiological cues by regulating ...

In this Review, familial and sporadic neurological disorders reported to have an etiological link with DNA repair defects ... single-strand break; TCR, transcription-coupled repair.

More information: Wei Wu et al, VGLL3 modulates chemosensitivity through promoting DNA double-strand break repair, Science ...

44 141 330 6256 Fax: +44 141 330 5602 [email protected] The approximate 8.0 kbp dsDNA genome is transcribed in one direction from one DNA strand. Transcription is polycistronic yielding RNAs ...