Organelles in the endocytic pathway are composed of a mosaic of structural and functional regions. These regions consist, at least in part, of specialized protein–lipid domains within the plane ...

A new pathway in endocytosis has been identified in budding yeast, demonstrating the role of a specific compartment of the trans-Golgi network.

In addition, the endocytic pathway is not completely blocked in yeast cells lacking all Rab5 genes, suggesting the existence of an unidentified route that bypasses the Rab5-dependent endocytic ...

The new endocytic mechanisms identified in this study are suggestive of similar transport pathways (compartments) in mammalian cells.

This study elucidated how exogenous RNAs enter fungi and identified the core components involved in fungal endocytic pathway.

This novel endocytic recycling pathway employed a distinct set of molecular machinery to generate the recycling carriers and facilitate the unexpected kiss-and-run membrane fusion.

Extensive sorting of internalized molecules also takes place along the endocytic pathway: selected molecules are returned to the surface of the cell (e.g., recycling receptors), whereas others are ...

Eleven million Euros are provided under this program to the project "Endotrack" (Tracking the endocytic routes of polypeptide growth factor receptor complexes and their modulatory role on ...

These vesicles are then fused with early endosomes, which are the main sorting compartment of the endocytic pathway.

The researchers used three endocytic pathways as markers to sort out 29 non-small cell lung cancer (NSCLC) lines into two distinct clusters characterized by their endocytic dysfunction.

GMAB is an adaptive technology that uses a novel, cell-penetrating antibody to specifically deliver nucleic acid payloads to select cells while distinctly avoiding the endocytic pathway.