Epigenetic inheritance concerns the mechanisms that ensure transmission of epigenetic marks from mother to daughter cell. Chromatin modifications and nuclear organization are candidates for ...

These results may also have practical implications for future generations through epigenetic inheritance, as many of the observed epigenetic associations are related to brain development.

The authors claim it is the first experimental evidence for transgenerational epigenetic inheritance using methylation-edited mice. “It’s kind of a dream experiment,” says Patrick Allard, an ...

The nuclear architecture and long-range interactions are likely to contribute to inheritance of epigenetic information. The concerted action of trans-acting factors and the chromatin landscape ...

Researchers at University of California San Diego School of Medicine have published results that shed new light on an old question: what causes aging at the molecular level? Their findings, published ...

Of particular interest is the silencing of tumor-suppressor genes by epigenetic alteration. Recent progress in understanding epigenetic modification and gene silencing has led to new opportunities ...

Teresa Lee's Research Lab-Epigenetic inheritance of complex traits like longevity; the role of chromatin in regulating gene expression and development. Development and maintenance of the nervous ...