COG Complex: A multi-subunit assembly that facilitates retrograde vesicular transport within the Golgi apparatus, crucial for maintaining enzyme localisation and glycosylation fidelity.

Our cells carry out hundreds of thousands of important functions every day, all of which are carefully orchestrated at a microscopic scale. However, the precise mechanisms that influence the luminal ...

Golgi glycosylation malfunction and dysregulation has also been implicated in the proliferation of cancer cells and disease progression.

Researchers found that virus-like particles produced by co-expression of SARS-CoV-2 S, membrane, envelope, and nucleocapsid proteins contain S glycoproteins, which are modified by complex ...

Proteins usually undergo modifications during or after their synthesis in the endoplasmic reticulum (ER) and Golgi apparatus network inside eukaryotic cells. One such modification is glycosylation ...

When attached to target proteins, this sequence enhances their interactions with glycosylation enzymes in the Golgi apparatus, leading to significantly increased galactosylation and sialylation ...

Proteins usually undergo modifications during or after their synthesis in the endoplasmic reticulum (ER) and Golgi apparatus network inside eukaryotic cells. One such modification is glycosylation ...

In addition, the cells showed defects in protein glycosylation, a major enzymatic reaction performed in the Golgi and trans-Golgi network.