In a study published in the journal Science, researchers at Baylor College of Medicine, Université de Strasbourg, Université Paris Cité and collaborating institutions reveal how DNA gyrase ...

First step to untangle DNA: Supercoiled DNA captures gyrase like a lasso ropes cattle Date: April 11, 2024 Source: Baylor College of Medicine Summary: Researchers reveal how DNA gyrase resolves ...

Using high-resolution cryo-electron microscopy researchers uncovered unprecedented detail of gyrase’s action on DNA.

In this issue, Nöllmann and colleagues report single-molecule analyses of DNA gyrase action on supercoiled DNA under different levels of strain. Surprisingly, they found that gyrase changes its ...

New research has revealed how DNA gyrase resolves DNA entanglements – by getting lassoed by the supercoiled DNA.

The team of researchers combined their expertise to study the interactions of DNA gyrase with DNA minicircles using recent technology advances in electron cryomicroscopy, an imaging technique that ...

DNA gyrase is a target for a number of different antibiotics, but with several 'super-bugs' emerging that are resistant to antibiotics, there is more urgent need to understand how bacterial cells ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...

It’s long been known that DNA gyrase plays a role in untangling the overwinding, but the details were not clear. DNA minicircles and advanced imaging techniques reveal first step to untangle DNA “We ...