Herpes stromal keratitis (HSK) is a potentially blinding ... Secretion of VEGF by HSV-infected epithelial cells leads to in-growth of lymph and blood vessels. Largely CD4 T-cell mediated ...

epithelial defects and, in worst-case scenarios, ulceration,” Ahmad said. The more common causes are infections, such as herpes zoster ophthalmicus and herpes simplex keratitis. Systemic causes ...

[103] In a retrospective case series of seven children (aged 6 weeks to 5 years) with HSV epithelial keratitis, all symptoms resolved within 2 weeks of systemic acyclovir treatment. There were no ...