This means looking out for "crusting and healing of all prior blisters and open sores in the skin," says Oza. More: Hand, foot, and mouth disease can be painful and inconvenient. Here's what it is.

"Hand, foot, and mouth disease can cause painful oral ulcerations and an itchy skin rash," says Dr. Kellie Kruger, a board-certified physician in internal medicine and pediatrics at Mayo Clinic in ...