To explore whether overexpression of the small heat shock protein HSP20 in rat cardiomyocytes protects against simulated ischemia/reperfusion (SI/R) injury. Recombinant adenovirus expressing HSP20 ...

What happens to a child's body when they sit in class during a heatwave and what does this mean for their long-term health?

Overexpression of heat-shock protein 20 in rat heart myogenic cells confers protection against simulated ischemia/reperfusion injury. Acta Pharmacol Sin 2005; 26: 1076–80. Article CAS Google Scholar ...

Dr Hoaglin also likes another hot room effect – an increase in melatonin production, that handy hormone which promotes good ...

Heat shock proteins play both a protective and a restorative role in the human body. These molecules are expressed when cells are stressed by heat, a lack of blood flow, or an influx of heavy metals, ...

Protein aggregation after heat shock is an organized, reversible cellular response Date: September 10, 2015 Source: University of Chicago Medical Center Summary: Protein aggregates that form after ...

A heat shock protein protects the cells against protein clumping. It degrades, however, over longer treatment periods.

Commentator Joe Wright is in his second year of medical school, and sometimes he can't believe how much science he's absorbed in the last year in a half. Here's one thing he's learned from science ...

Researchers have determined that heat shock protein 90 (Hsp90) can create diverse heritable traits in brewer's yeast by affecting a large portion of the yeast genome. The finding has led the ...

The human brain is comprised of two main types of cells, known as neurons and glia. The first are responsible for ...

Heat shock proteins (HSPs) chaperone other cellular proteins, guarding them from going astray, folding improperly or misassembling while forming larger aggregates, as in the examples below.

Over the last 20 years there has been a growing appreciation for the role of HSF1 in cancer pathophysiology. Recent work has shown a role for HSF1 in cancer beyond the canonical heat shock response.