The S. cerevisiae Pif1 helicase acts at G4 motifs 64, and members of the Pif1 DNA helicase family are particularly efficient in vitro unwinders of parallel intramolecular G4 substrates 59.

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

DHX36 specifically binds to G4 structures on DNA (particularly in rDNA regions and ... Novel roles of nucleic acid G-quadruplex mediated by helicase DHX36 during mammalian oocyte growth and ...

The G4-DNA structure can therefore be involved in both the enhanced and impairment of transcription in active neurons, based on their activity, to enable different memory states.

The G4-DNA structure can therefore be involved in both the enhancement and impairment of transcription in active neurons, based on their activity, to enable different memory states.

DNA replication is a complex process in which a helicase ring separates the DNA molecule's two entwined and encoded strands, allowing each to precisely reproduce its missing half.

Dynamic DNA structures and the formation of memory Date: May 1, 2024 Source: University of Queensland Summary: An international collaborative research team has discovered that G-quadraplex DNA (G4 ...

The human genome encodes 95 helicase forms. Even the microscopic E. coli bacterium has more than a dozen helicases. When something goes wrong with helicases, it can cause health problems.

Intriguing evidence for yet another role of DDX3X has emerged, this time in the context of the DNA damage response. Disruption of this helicase impairs DNA repair pathways, leading to an accumulation ...

After a zap of voltage sends the conjugated molecule through the nanopore, the Hel308 helicase walks on the DNA section, pulling both the DNA and the attached peptide back through the nanopore. As ...