A new study has unveiled the intricate 3D genome structure of Brassica crops, thanks to an optimized Bridge Linker ...

A generative AI-based technique can predict thousands of 3D genomic structures in just minutes, enabling researchers to more ...

To explore the 3D morphology of the existing chromosomes, Aiden modified an in situ Hi-C protocol, dubbed PaleoHi-C. 2 This technique, adapted for ancient samples and combined with DNA sequencing, ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D ...

Additionally, by combining Hi-C with other DNA and RNA sequencing techniques, scientists can gain new perspectives on how soil drying influences the relationships between phages and their hosts.

So how, then, do researchers determine the sequence of A's, G's, C's, and T's that comprise the genome? The answer is that they've had to develop a new process, what Bruce Birren of MIT's ...

MIT chemists have now developed a generative AI-based method to predict these 3D genome structures ... nucleus by breaking DNA into fragments and sequencing them. Hi-C can be applied to single ...

The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

Because the research team used an integrated WGS approach, they could sequence patient tumor and non-tumor DNA in tandem in search of variants that carry information about patient predisposition to ...