A recent review by Prof. Zhu Bing and Associate Professor Xiong Jun from the Institute of Biophysics of the Chinese Academy ...

In this Review we take advantage of evidence from recent genetic, biochemical and microarray studies to explore the relationship between DNA methylation and histone modification, particularly ...

We review the aberrant covalent histone modifications observed in cancer, and discuss how these epigenetic changes, caused by alterations in histone-modifying enzymes, can contribute to the ...

The review discusses how epigenetic modifications such as DNA methylation, histone modifications, and RNA modifications are associated with cancer development.

The review discusses how epigenetic modifications such as DNA methylation, histone modifications, and RNA modifications are associated with cancer development.

By integrating histone and non-histone lactylation, this review opens new directions for investigating how metabolism-driven protein modifications reshape cellular behavior and how these pathways ...

Fruit ripening determines shelf life and consumer appeal, yet the molecular switches that control this process remain ...

A recent study has revealed promising targets for treating childhood acute myeloid leukaemia (AML) driven by NUP98 fusion ...

Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

Modification of histone tails, by acetylation, methylation or phosphorylation, affects the local chromatin structure and the transcriptional regulation of adjacent genes. Pericentric heterochromatin ...

Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone modification (called “writers,” “erasers,” ...

Posttranslational modifications on histone proteins play a role in regulating chromatin structure and gene expression. Now another so-called histone mark can be added to the list: lysine benzoylation.