The paper, by W. Li at Wuhan University in Wuhan, China, and colleagues was titled, "A methylation-phosphorylation switch determines Plk1 kinase activity and function in DNA damage repair." ...

This image depicts the ... that are intermediates in the DNA demethylation process. These modifications play important roles in DNA methylation dynamics, gene expression, and cell differentiation.

Post implantation, de novo methylation begins (red circles), mediated primarily by DNA (cytosine-5-)-methyltransferase-3alpha (DNMT3A) and -3beta (DNMT3B) (top). When methylation affects CpG ...

Aging is accompanied by specific patterns of epigenetic marks that attach to DNA and can be studied to understand subcellular aging mechanisms Disclaimer: AAAS and EurekAlert! are not responsible ...

The marks influence which genes are expressed or what levels they’re expressed at. Most methylation occurs at specific locations in the DNA, typically on a cytosine (C) that sits next to a guanine (G) ...

DNA methylation is a fundamental epigenetic mechanism in which a methyl group is added onto a nucleotide, commonly cytosine. DNA methylation affects many biological processes, including gene ...

5-Methylcytosine is a modified nucleobase formed by the enzymatic addition of a methyl group to the 5th carbon of cytosine. This modification is involved in epigenetic regulation, gene silencing, and ...