Allogeneic stem cell transplantation can cause a loss of protective goblet cells from the colon's inner lining, which can be fatal. But boosting those cells beforehand could improve the outcome.

Figure 1: Notch signalling pathway components are expressed in crypts of the small intestine. Figure 3: Conversion of proliferative crypt cells into post-mitotic goblet cells by the γ-secretase ...

Goblet cells perform the same function in people as in mice, Newberry said, based on his team's analysis of healthy human intestinal tissue removed from patients undergoing weight-loss surgery.

Both microbial and host inflammatory factors modulate sulfomucin production in a human cell line, LS174T, that models intestinal goblet cells, a team of scientists at the University of Illinois ...

Researchers identify unexpected player in intestinal immunity Date: March 14, 2012 Source: Washington University in St. Louis Summary: With every meal, immune cells in the intestine stand like ...

The scientists reported on their findings in Cell Reports, in a paper titled “BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell status.”. The small ...

The answer appears to lie in the balance of microbes that live in our intestine—and a specific protein secreted by intestinal ...

The intestinal epithelium consists of four main specialized cell lineages: absorptive enterocytes and three secretory cell types known as enteroendocrine, Paneth, and goblet cells. But a rare ...

After 28 days, these progenitors had formed into three-dimensional tissue that closely resembled human intestinal tissue, complete with the usual enterocytes, goblet, Paneth and enteroendocrine cells.

Intestinal stem cells rejuvenate daily so bowels will stay healthy and function normally, but a new study in Cell Reports suggests they also age along with people and lose their regenerative capacity.