Edited by: Thomas W. Durso and Karen Young Kreeger M. Hochstrasser, "Ubiquitin, proteasomes, and the regulation of intracellular protein degradation," Current Opinion in Cell Biology, 7:215-23, 1995. ...

Intracellular constituents such as proteins and organelles are turned over by unremitting synthesis and degradation. This dynamic turnover is critical for homeostasis, development, and environmental ...

“Protein degradation is based on intracellular processes, and it builds on the cell's natural system for recycling unneeded or defective proteins. This disposal process, which is called the ubiquitin ...

Autophagy is a cellular degradation pathway for the clearance of damaged or superfluous proteins and organelles. The recycling of these intracellular constituents also serves as an alternative ...

Proteins in cells are highly flexible and often exist in multiple conformations, each with unique abilities to bind ligands.

The following is a summary of “Novel protein C variant p.C101F results in early intracellular degradation that drives type I ...

A research team at POSTECH (Pohang University of Science and Technology) has successfully developed a super-photostable ...

and is trying to clarify various questions related to intracellular degradation. A common mechanism of eukaryotes, from yeast to humans. It prevents the accumulation of abnormal proteins. And it also ...

A new role of calcium in the development of muscles has been reported by two RIKEN biologists. Stress is generally damaging and destructive, but it can sometimes spur productivity and creation. This ...

3) Inside macrophages, Mycobacterium tuberculosis dodges intracellular degradation by secreting virulence factors ... HIV-1 expresses viral factors such as the negative factor (Nef) protein. In the ...