The term congenital lactic acidosis (CLA) refers to a group of inborn errors of ... molecular identification of specific enzyme defects in the majority of infants and children with CLA. Most ...

Diagnosis. Lactic acidosis associated with prolonged exposure to linezolid. Management. Discontinuation of linezolid. Lactic acidosis is a common disorder associated with disturbed acid–base ...

Great Ormond Street Hospital is a tertiary referral children’s hospital and the specialist nature ... only 9% were found to have congenital lactic acidosis, compared to 34% of patients who were in the ...

However, its use can sometimes lead to serious complications, particularly metformin-associated lactic acidosis (MALA) and acute kidney injury (AKI). MALA is a rare but potentially life ...

Objective: To compare the prognostic abilities of lactic acidosis and hyperlactatemia and determine the influence of metabolic acidosis when attempting to predict the outcome of septic patients using ...

Its physiological meaning has not yet been definitely determined, but the most common explanation is a failure of the body’s buffering mechanisms which leads to metabolic (lactic) acidosis. It was ...

Metformin-associated lactic acidosis (MALA) is a rare and potentially life-threatening complication of metformin use. It typically occurs in patients who are diabetic and also have other risk factors ...

Although thrombocytopenia and peripheral neuropathy are frequently encountered following prolonged administration of linezolid, lactic acidosis is a rare adverse drug reaction. We present the case of ...