Ten years ago, the cell biological role of lipid rafts was controversial owing to limited methodology and confusing nomenclature. Through technical advances, our concept of lipid rafts has evolved ...

Tiny structures made of lipid molecules and proteins have been believed to wander within the membrane of a cell, much like rafts on the water.

Membrane cholesterol–sphingolipid ‘rafts’, which are characterized by their insolubility in the non-ionic detergent Triton X-100 in the cold, have been implicated in the sorting of certain ...

Charge-dependent interactions of monomeric and filamentous actin with lipid bilayers. Proceedings of the National Academy of Sciences, 2020; 201914884 DOI: 10.1073/pnas.1914884117; ...

image: Simulation of actin-binding to the lipid membrane with negatively charged lipids (orange). Blue color indicates calcium concentrations. view more Credit: S-J Marrink, University of Groningen ...

The team’s studies linked prolonged suppression of signaling in membrane lipid rafts with what they call the “constellation of symptoms known as antidepressant discontinuation syndrome. ...

Lipid rafts are shown to participate in lysosomal reproduction, and some lysosomal storage diseases are proposed to result from the accumulation of lipids in late endosomal/lysosomal compartments.

That assembly and release of HIV-1 particles takes place at the plasma membrane has been established for some time. It has also been suspected that the process additionally requires lipid rafts — ...