In this 6-week, double-blind trial, 585 patients were randomized to losartan/ hydrochlorothiazide or losartan as monotherapy and titrated as needed at 2-week intervals to reach goal blood pressure ...
and 50.8% losartan 50mg plus hydrochlorothiazide. The additional antihypertensive therapy included, in order of decreasing frequency, ß-adrenoceptor antagonists, diuretics (other than the ...
investigated the combined effects of a low-sodium diet and the diuretic hydrochlorothiazide on proteinuria and blood pressure in Dutch patients receiving the angiotensin-receptor blocker losartan.
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