Co-located cell types help drive aggressive brain tumors, study finds
A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, ...
eLife2d
Multi-Omics Single-Cell Analysis Reveals Key Regulators of HIV-1 Persistence and Aberrant Host Immune Responses in Early Infection
This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...
Mapping brain development at the protein level in unprecedented detail
Researchers at the University of Virginia have created the first comprehensive protein-level atlas of brain development, ...
GEN11mon
Harnessing Single-Cell RNA Sequencing to Study Retinal Ganglion Cell Regeneration in Optic Neuropathies
In the first presentation of this GEN webinar, our expert speaker Devansh Agarwal will present results from a study and how the scientists generated RGC-like induced neurons in under a week by ...
BioTechniques7y
Sequencing reveals new cell types for the BRAIN initiative
One of the top priorities of the BRAIN initiative is identifying and providing experimental access to the different cell types in the brain, as well as determining their roles in health and disease.
eLife9d
Sleep need driven oscillation of glutamate synaptic phenotype
Sleep's role to down-scale glutamate, excitatory, frontal cortical synapses is extended to include an up-scaling of metaplastic LTP potential, in recovery from prolonged waking induced saturation of ...