What's the difference between mRNA and pre-mRNA ... Our knowledge of RNA splicing is quite new. Nonetheless, because nearly all eukaryotes have introns and share mechanisms of RNA splicing ...

The answer: alternative splicing. A critical finding regarding the prevalence of alternative splicing was that a majority of human genes produce a wide variety of messenger RNAs (mRNA) that in ...

Research into splicing mechanisms and patterns is essential for decerning fundamental biological principles, as well as clarifying the molecular basis of many diseases and developing new therapies. 2 ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, ...

Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) and the Germans Trias i Pujol Research Institute (IGTP ...

Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) and the Germans Trias i Pujol Research Institute (IGTP ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is .

RNA breaks destined for repair are inflicted by sequence-specific or structure-specific endoribonucleases during physiological RNA processing (e.g. tRNA splicing; kinetoplast mRNA editing ... by a ...

in thinking about novel mechanisms of how quantitative regulation occurs in the cell.” Next, Guttman and his team want to uncover how genome structure organizes to enable the specific and precise ...

Spliceosomes act as an editing tool, helping to make sense of the fragmented messages stored in pre-mRNA ... mechanism of minor intron recognition and sheds light on the evolution of the splicing ...

Individual genes express multiple mRNAs by pre-mRNA alternative splicing ... that regulation of alternative splicing has a huge impact on gene function and there is a great deal to learn about ...