Microglia replacement therapy helps treat people with a rare genetic condition called ALSP, suggesting the approach could ...

Replacing defective microglia can halt ALSP—a fatal neurodegenerative disease—in mice and humans, offering hope for broader brain therapies.

Alzheimer's disease progression linked to microglia fat metabolism, potential new treatment target identified in recent study ...

Glial cells support neurological structures, function, cognition, behaviours, physical skills, and motor coordination.

A study reveals that a common genetic mutation doubles the risk of dementia in men, linking it to problems with iron ...

INDIANAPOLIS - Indiana University School of Medicine researchers have identified a portfolio of novel drug targets that may accelerate promising ...

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive neurological disease with an average age of onset of ...

PDE-1905, offers high-resolution imaging of neuroinflammation by targeting a key enzyme inside microglia, the brain’s immune cells.

The study, published March 6 in Nature Medicine, shows that the brain’s immune cells, called microglia, play a more powerful ...

The researchers discovered that STING, an immune molecule meant to protect the brain, may actually be making things worse as ...

How immune cells in the brain coordinate their work Infections in the brain can have serious consequences and are often fatal. The immune defence system works differently here than in the rest of the ...

Microglia: How the brain’s immune cells may be causing dementia. They fight invaders, clear debris and tend neural connections, but sometimes microglia go rogue.