Amazingly, the molecular breakthroughs in autophagy ... to involve a directed targeting-and-sequestration mechanism. During nonspecific autophagy (see figure part a), sequestration begins with ...

While the process has been known since the early 1960s, the molecular mechanisms of autophagy were deduced by Ohsumi and his team by studying yeast cells and identifying the genes that drive it.

Analysis of the molecular mechanism of autophagy in vertebrates is progressing. In the “MIZUSHIMA Intracellular Degradation” ERATO project, a novel autophagy factor that does not exist in yeast was ...

As a result, autophagy is a fundamental defense mechanism employed by cells to control and clear ... Once a month, we bring you the stories behind news-worthy molecular biology research. Experts from ...

On a molecular level ... 5d) may serve either of two purposes, in teleological terms. First, autophagy may constitute a mechanism through which the cell destined to die initiates its catabolism ...

Researchers from the Institute of Oceanology of the Chinese Academy of Sciences, in collaboration with scientists from the ...

We hypothesize that some of these autophagy related proteins are crucial for the maintenance of progenitor stem cells in endometrium and thus, we are interested in evaluating the underlying molecular ...

Using advanced molecular biology and genetic tools ... future studies should focus on understanding the precise mechanisms of autophagy regulation and its therapeutic application in diverse ...

Dinoflagellates play crucial roles in aquatic ecosystems, particularly as major contributors to harmful algal blooms. They ...