Max-Planck-Gesellschaft. (2014, December 2). Ryanodine receptor: Calcium channel in muscle cells. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2014 / 12 ...

Specifically, the release of stored calcium causes muscle cells to contract, a process called excitation-contraction coupling (ECC), while lowering the concentration of the chemical depolarizes ...

It mediates calcium release from the sarcoplasmic reticulum, a calcium-storing organelle in muscle cells, a process vital for muscle function. Mutations in the RyR1 gene can affect the channel’s ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse ...

Voltage‐gated calcium channels are integral transmembrane proteins that convert membrane depolarisation into a multitude of intracellular responses, ranging from muscle contraction and ...

Ferulic acid suppresses ileal smooth muscle contraction by inhibiting calcium ion influx through voltage-dependent calcium channels. This action may help prevent or treat excessive intestinal ...

A research team at Toho University has revealed that ferulic acid (FA), a polyphenol abundant in rice bran, suppresses intestinal smooth muscle contractions by inhibiting voltage-dependent calcium ...

Calcium helps regulate muscle contraction. ... Avoid supplement use while taking calcium channel blockers, which are a common type of medication for lowering blood pressure.

Calcium ions, which are ultimately responsible for the contraction of muscle cells, are released from storage organs and flow through these ion channels.

Researchers uncover the dual role of the fifth transmembrane segment (S5) in the type 1 ryanodine receptor (RyR1) channel, crucial for muscle function. These findings offer new insights into improved ...