Max-Planck-Gesellschaft. (2014, December 2). Ryanodine receptor: Calcium channel in muscle cells. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2014 / 12 ...

Specifically, the release of stored calcium causes muscle cells to contract, a process called excitation-contraction coupling (ECC), while lowering the concentration of the chemical depolarizes ...

The store-operated calcium channel (SOC) located in the plasma membrane (PM) mediates capacitative entry of extracellular calcium after depletion of intracellular calcium stores in the endoplasmic ...

It mediates calcium release from the sarcoplasmic reticulum, a calcium-storing organelle in muscle cells, a process vital for muscle function. Mutations in the RyR1 gene can affect the channel’s ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse ...

Voltage‐gated calcium channels are integral transmembrane proteins that convert membrane depolarisation into a multitude of intracellular responses, ranging from muscle contraction and ...

A research team at Toho University has revealed that ferulic acid (FA), a polyphenol abundant in rice bran, suppresses intestinal smooth muscle contractions by inhibiting voltage-dependent calcium ...

Ferulic acid suppresses ileal smooth muscle contraction by inhibiting calcium ion influx through voltage-dependent calcium channels. This action may help prevent or treat excessive intestinal ...

Calcium ions, which are ultimately responsible for the contraction of muscle cells, are released from storage organs and flow through these ion channels.

Researchers uncover the dual role of the fifth transmembrane segment (S5) in the type 1 ryanodine receptor (RyR1) channel, crucial for muscle function. These findings offer new insights into improved ...