the N-terminal Ig-motif is responsible for sequence-specific DNA binding and the linker region that connects the two Ig-motifs has the corresponding role of the C-terminal tail that extends from ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms.