Freshly isolated NK cells, but not natural killer T cells or ... of a new member of the TNF family that induces apoptosis. Immunity 3, 673–682 (1995).

A major breakthrough in the fight against cancer has just been achieved. An innovative method, successfully tested in the ...

Intracellular checkpoint molecules like BIM, which mediates apoptosis in NK cells, can be targeted to enhance antitumor responses. The absence of BIM in NK cells has been shown to increase their ...

Moreover, researchers are investigating ways to enhance the cytotoxic capabilities of NK cells. For instance, studies have shown that targeting the mitochondrial apoptosis pathway can ...

Scientists from the University of Pennsylvania have developed an innovative cancer treatment using small extracellular ...

Nano-sized, tumor-targeting particles induced self-destruction of cancer cells in preclinical studies. A new twist on a decades-old anticancer strategy has demonstrated significant potential against v ...

When activated, DR5 can trigger the death of these cells by a self-destruct process called apoptosis ... the team used sEVs made by natural killer (NK) cells, a type of immune cell that frequently ...

An approach using engineered small extracellular vesicles from NK cells to DR5 could be a promising strategy for solid tumors ...

Engineered extracellular vesicles show promise in targeting cancer cells and immunosuppressive stromal cells, offering a groundbreaking dual-action cancer therapy with minimal toxicity.