So now it becomes apparent how NMR can help in chemistry. It can decipher these energy difference within the sample, thus can find the atomic structure of substances. But that is not all. In all ...

NMR can identify different nuclei in a molecule and analyze large proteins and other large molecules using three dimensional (3-D) techniques. This instrument provides powerful information for the ...

and user training in simple 1D and 2D NMR data acquisition and analysis is also available. Expert services are available to determine small molecule identity or conformation, to identify and quantify ...

Unfortunately, many 1H-NMR spectra are severely overlapped due to the multiplet structure caused by homo-nuclear scalar couplings. "Pure shift" NMR spectra, also known as broadband homonuclear ...

To the Editor: NMR spectroscopy is currently the only technique for determining the solution structure of biological macromolecules. This typically requires both the assignment of resonances and a ...

In a collaborative high-throughput effort to determine the three-dimensional structures of small proteins, two studies demonstrate that X-ray crystallography and nuclear magnetic resonance (NMR ...

Structure determination by NMR typically requires a protein concentration of 0.5 mM or greater, stable for several days at the desired temperature, usually 20-40 o C. Proteins and peptides should be ...

The NMR and Drug Metabolism Core has developed rapid and efficient approaches to investigate metabolism, metabolic stability, pharmacokinetics (PK), and chemical structure identification of small ...

The new 1.2 GHz NMR complements the existing 800 MHz NMR in Basel and other high-field NMRs for protein structure determination, measurement of protein dynamics, ligand binding studies ...

This work includes using in cell NMR, a technique to study the structure and dynamics of proteins within living cells. I currently study intrinsically disordered proteins using solution NMR. Proteins ...

Nearly every element has at least one isotope that is NMR active. Since then, NMR spectroscopy has become an indespensible tool for the determination of molecular structure, the study of molecular ...