influences feeding and is implicated in the sleep disorder narcolepsy. Subsequent studies have illuminated many aspects of the circuitry of the hypocretin (also called orexin) system, which also ...

Interestingly, orexin deficiency is a leading cause of narcolepsy, a sleep disorder marked by episodes of excessive daytime sleepiness. In people with short sleep, however, orexin production ...

Horsnell has narcolepsy, a sleep disorder that makes it ... we think happens is the body’s immune system attacks the part of ...

Parasomnias are disruptive sleep disorders that can occur during arousals ... that make them feel sleepy.Quviviq is known as an “orexin receptor antagonist.” It blocks the wakeful effect ...

no autoantigens have ever been found in narcolepsy Narcolepsy is a chronic sleep disorder linked with disturbances in the hypocretin (also known as orexin) system. In humans, studies suggest that ...

TAK-994 was in a pair of phase 2 trials as a treatment for excessive daytime sleepiness in narcolepsy, a rare long-term brain disorder that ... the role of orexin in sleep pathways.

Idorsia has become the first drugmaker in the EU to claim approval for a drug for chronic insomnia in the dual orexin receptor antagonist class, ahead of rival drugs from Merck & Co and Eisai.

Orexin-2 receptor ("OX2R") partial agonist: Aids in restoring sleep-wake cycles and enhancing cognitive stability, which are significantly disrupted during opioid withdrawal. Fentanyl, a synthetic ...