The EMBO Journal4d
Haploinsufficient phenotypes promote selection of PTEN and ARID1A-deficient clones in human colon
Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...
Medscape12y
Differences in Molecular Genetics Between Pediatric and Adult Malignant Astrocytomas
Mutations can differ by age; IDH1 mutations common in adult low-grade glioma are rare in pediatric low-grade glioma, while EGF receptor variant III mutations are common in adult high-grade glioma ...
Hosted on MSN6d
Daily, Long-Term Aspirin Use Reduces Colorectal Cancer Recurrence
Adjuvant treatment with 160 mg aspirin daily for three years cuts recurrence rates in patients with colorectal cancer with ...
MedPage Today15d
Study Finds Actionable Mutations in Brain Mets of Breast Cancer Patients
In addition to this, we also assessed the prognostic values of these alterations, and specifically in the HER2-positive breast cancer brain metastasis, we observed that the presence of PIK3CA ...