Results described in the paper more generally suggest that the molecular mechanism of programmed cell death has been conserved evolutionarily from worms to mammals. "Concerning evolutionary ...

Researchers reveal that gut microbiota influence the effectiveness of immune checkpoint inhibitors (ICIs) in cancer treatment ...

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed.

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

A treatment for patients living with advanced non-small cell lung cancer (NSCLC) who failed two or more standard-of-care (SOC ...

A group of Penn scientists has developed a new method to remotely control engineered cells inside the human body using heat.

After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do not divide, are involved in the aging process, and are resistant to cell ...

Aligos Therapeutics Inc. has disclosed programmed cell death 1 (PDCD1; PD-1; CD279) and/or PD-1 ligand 1 (PD-L1; CD274) and/or PD-1/PD-L1 interaction inhibitors reported to be useful for the treatment ...

A phase 3 clinical trial has shown that adding a targeted immunotherapy drug to chemotherapy dramatically improved – almost ...

Tislelizumab is BeiGene’s programmed cell death protein 1 (PD-1) checkpoint inhibitor and Anktiva is an interleukin-15 (IL-15 ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively ...