Pigmented Villonodular Synovitis (PVNS) is a rare condition that causes painful swelling in certain joints. It can cause large, noncancerous tumors to form at these joints. Estimates show that ...

In pigmented villonodular synovitis (PVNS), the synovium thickens, forming a growth called a tumor. PVNS isn’t cancer, but it can cause complications if left untreated. Read more.

Potential therapy for patients with advanced pigmented villonodular synovitis. ScienceDaily . Retrieved April 24, 2025 from www.sciencedaily.com / releases / 2014 / 05 / 140514182536.htm ...

(BPT) - TGCT stands for tenosynovial giant cell tumor, which is also sometimes called pigmented villonodular synovitis (PVNS) or giant cell tumor of the tendon sheath (GCT-TS). To most of us this ...

‌Pigmented villonodular synovitis ... just one joint is involved. Usually, this is the knee, followed by the ... Diffuse-type tenosynovial giant cell tumor (pigmented villonodular synovitis) ...

The results are preliminary, but so far 11 of 14 evaluable patients have responded to the drug. They experienced a mean reduction in tumor volume of 61%, and rapid and substantial improvements in ...

A 22-year-old woman came to us with a 2-week history of recurring stiffness of the left knee joint. MRI of the knee revealed a tumor arising from the Hoffa fat pad. The cause was a proliferative ...

In this Healio interview, Sandra D’Angelo, MD, discussed two “interesting” studies for pigmented villonodular synovitis, or PVNS, presented at the Connective Tissue Oncology Society Annual ...

PVNS is a rare, locally aggressive tumor of the synovium. It is characterized by local over-expression of CSF-1, which recruits macrophages into the joints, forming the non-malignant tumor mass.

In pigmented villonodular synovitis, the synovium swells. It isn’t cancer but can cause complications. ... In arthroscopy, the surgeon will remove the tumor from the front of your knee.

Clinical Snapshot A Rare Cause of Knee Joint Stiffness. Dtsch Arztebl Int 2020; 117: 792.DOI: 10.3238/arztebl.2020.0792a. Lahner, M; ; ...