Every cell in the body normally has its fixed place as part of a tissue structure. Except for a few cell types, such as blood ...

Key among these is the activation of signaling by RHO (another member of the RAS superfamily) and the up-regulation of kinases, some of which have the same substrates as ERK. Studies are needed to ...

Bidirectional signaling also makes things a little more ... turning on Eph receptor forward signals that then target GEFs for Rho and GAPs for Rac and Cdc42 to produce GTP-bound Rho and GDP ...