TGF-b is a cytokine that promotes collagen production (MassaguE9, 1998). AP-1 is a transcription factor that inhibits collagen production and up-regulates collagen breakdown (Kang, Fisher ...

Transforming growth factor-β (TGF-β) stimulation of Type I collagen gene (COL1A2) transcription involves the Smad signal transduction pathway, but the mechanisms of Smad-mediated transcriptional ...

Growth factor serums may be the key To boosting your skin’s collagen, and here's why you'll love them. Check out our options to shop starting at $16.

The M10 peptide reduces collagen production and reverses fibrotic damage due to systemic sclerosis (SSc)-related interstitial lung disease (ILD), preclinical findings suggests. ILD is one of the ...

"The anti-FSTL1 mnAbs ameliorated bleomycin-induced pulmonary and dermal fibrosis in mice, as reflected by biochemically determined 50% reductions in collagen," said Jiang. Similarly, "they ...

Collagen 1 is increased in both the intracellular and extracellular compartments whilst α-SMA incorporation into ... and representative images of stained FMT markers in TGF-β1 stimulated cells (B).

Background: Elevated levels of TGF-b expression are associated with poor prognosis in breast cancer and TGF-b is an immunosuppressive cytokine that is thought to play an essential role in tumor immune ...

One in 15,000 people in the UK are estimated to have osteogenesis imperfecta (OI). It is an inherited condition, where abnormalities in the genes controlling collagen affect the bone's strength.