There are two important regulators of collagen production: transforming growth factor (TGF)-b and activator protein (AP)-1. TGF-b is a cytokine that promotes collagen production (MassaguE9 ...
The most potent stimulus to collagen I production is TGF-beta, which is derived from both paracrine and autocrine sources. Lipid peroxidation products are emerging as important stimuli to ECM ...
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