TGF-b is a cytokine that promotes collagen production (MassaguE9, 1998). AP-1 is a transcription factor that inhibits collagen production and up-regulates collagen breakdown (Kang, Fisher ...

Collagen-induced arthritis (CIA) is mediated by self-reactive CD4+ T cells that produce inflammatory cytokines. TGF-β2-treated tolerogenic antigen-presenting cells (Tol-APCs) are known to induce ...

Growth factor serums may be the key To boosting your skin’s collagen, and here's why you'll love them. Check out our options to shop starting at $16.

Collagen 1 is increased in both the intracellular and extracellular compartments whilst α-SMA incorporation into ... and representative images of stained FMT markers in TGF-β1 stimulated cells (B).

1 Tasanen K, Tunggal L, Chometon G, et al. Keratinocytes from patients lacking collagen XVII display a migratory phenotype. Am J Pathol 2004;164:2027–2038. 2 Buchroithner B, Klausegger A ...

The M10 peptide reduces collagen production and reverses fibrotic damage due to systemic sclerosis (SSc)-related interstitial lung disease (ILD), preclinical findings suggests. ILD is one of the ...

"The anti-FSTL1 mnAbs ameliorated bleomycin-induced pulmonary and dermal fibrosis in mice, as reflected by biochemically determined 50% reductions in collagen," said Jiang. Similarly, "they ...

Excessive transforming growth factor-β signaling is a common mechanism in osteogenesis imperfecta. Nature Medicine , 2014; DOI: 10.1038/nm.3544 Cite This Page : ...

One in 15,000 people in the UK are estimated to have osteogenesis imperfecta (OI). It is an inherited condition, where abnormalities in the genes controlling collagen affect the bone's strength.