Most currently available small molecules bind to and alter the activity of proteins, but a new study by Fedorova et al. demonstrates that tertiary RNA structures could also be therapeutic targets ...

In contrast, the research team introduced a fluorescence color-change strategy. Upon light exposure, tertiary amines form exciplexes with photoactivated naphthalimide molecules, which then ...

Small stereochemical changes can bring big distinctions to molecules like drugs, fragrances, and propellants. Switching the stereochemistry of a single substituent can change a rose-scented ...

1D 1 H-NMR analysis of food allergens allowed their classification into molecules with rigid, extended and ordered tertiary structures, molecules without a rigid tertiary structure and molecules which ...

Tertiary phosphines also played a role in turning water molecules into protons that helped achieve ammonia as the final product.

Tertiary amines, made of a nitrogen bound to three carbons, occur frequently in drug structures but are complicated to make. Synthesis often requires multiple steps under different reaction ...

The oxidized tertiary phosphines then activate water molecules via formation of a chemical bond between the phosphine's phosphorus atom and the water, yielding protons," said Nishibayashi.

The riboswitch must have a tertiary structure, because it likes to make a pocket and grab small molecules.

Noting that tertiary lymphoid tissues are commonly seen with acute kidney injury in mice and humans, Yanagita believes that the findings should be considered for drug discovery.

The aim of the study was to apply 1D 1H-NMR spectroscopy to structural analysis of a range of allergens from major allergen families and to assess its potential as an effective high throughput method.

The oxidized tertiary phosphines then activate water molecules via formation of a chemical bond between the phosphine’s phosphorous atom and the water, yielding protons,” said Nishibayashi.