On a focal basis, there were follicular structures containing colloid material in their lumen ... but their nuclei were strongly positive for thyroid transcription factor-1 (TTF-1; Fig.

Follicular thyroid cancer with bone involvement was associated with a significantly elevated risk for brain metastases among women.

Other slides may be air-dried for alcohol fixation and subsequent staining (excellent for detecting colloid ... fluid is more typical of a cyst of thyroid follicular origin.